Riley D Metcalfe The 44th Lorne Conference on Protein Structure and Function 2019

Riley D Metcalfe

Riley is a PhD student in A/Prof. Michael Griffin's laboratory at the Department of Biochemistry and Molecular Biology, Bio21 Institute, The University of Melbourne. Riley's PhD research focused on the structure of the cytokine Interleukin-11, the structure of it's signalling complex, and the mechanism of action of IL-11 signalling inhibitors. During his PhD, Riley has also contributed to other structural biology projects in the department, most notably a cryoEM study of the structure of the P. falciparum proteasome in complex with an activator (Xie, Metcalfe, Hanssen et al. Nature Microbiology, DOI: 10.1038/s41564-019-0524-4). Riley is currently completing his PhD, and will begin as a postdoctoral fellow in Dr. Ping Zhang's laboratory at the National Cancer Institute in Frederick, Maryland in mid-2020.